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CheMatech holds licences of powerful patented methods allowing the preparation of new or existing ligands.
The strengths of these methods:
WO2005000823: Process for preparing cis-8b-methyldecahydro-2a,4a,6a,8a-tetraazacyclopenta[fg]acenaphthylene, or cis-decahydro-2a,4a,6a,8a-tetraazacyclopenta[fg]acenaphthylene, cyclen, and functionalized cyclenes via cyclocondensation.
This patent describes a new synthesis of cyclen and bisaminal intermediate without purification steps and with very short reaction times.
WO03029228: A new process for preparation of C-functional nitrogen macrocycles.
This patent describes a new methodology for the preparation of C-functionalized macrocycles without using protection/deprotection sequences.
If your are interested in our technologies and in licensing, please contact us at info@chematech-mdt.com