Custom Synthesis and GMP production

Custom synthesis of chelating agents is a core component of CheMatech’s production capabilities. Our dedicated custom synthesis team delivers quantities ranging from milligrams to hundreds of grams, ensuring the flexibility to meet both research and preclinical needs.

We offer competitive pricing and reliable lead times, with products manufactured according to your exact specifications. Depending on your requirements, we can either follow your established synthetic route or develop and optimize a tailored process designed for cost efficiency and optimal performance.

CheMatech has extensive expertise in:

• Chelator synthesis
• Process development and optimization
• Synthesis of precursors for nuclear medicine (PSMA, FAPI, etc.)

Our production infrastructure includes:

• Automated glass reactors from 500 mL to 30 L
• Industrial rotavapor
• Flash chromatography systems
• Freeze dryer

CheMatech offers cGMP-compliant manufacturing services for the production of starting materials and intermediates. Our in-house facilities enable production from gram to kilogram scale within a dedicated cGMP environment, ensuring full compliance with regulatory standards. We operate in accordance with ICH Q7 and 21 CFR Part 210.

Our cGMP infrastructure includes:

• Production units (from 500 mL to 30 L)
• Purification units, including flash chromatography systems
• Drying units, including freeze dryers
• Controlled storage areas for raw materials and finished products
• Dedicated filling room

To support cGMP manufacturing, we offer comprehensive analytical development services:

• Broad range of analytical techniques: HPLC, MS, NMR, ion chromatography, Karl Fischer titration, ICP-MS/AES, bioburden, endotoxin
• Method development, qualification, and validation
•  Stability studies